Regional anesthesia
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Regional anesthesia · May 1992
Randomized Controlled Trial Clinical TrialAdding clonidine to mepivacaine prolongs the duration of anesthesia and analgesia after axillary brachial plexus block.
This study evaluates the effects of clonidine added to mepivacaine on the duration of anesthesia and analgesia after axillary brachial plexus block. ⋯ One hundred fifty micrograms clonidine added to mepivacaine for brachial plexus block prolongs the duration of anesthesia and analgesia. Our results suggest that this effect of clonidine is local rather than systemic.
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Regional anesthesia · May 1992
Randomized Controlled Trial Clinical TrialThe antiemetic efficacy and safety of prophylactic metoclopramide for elective cesarean delivery during spinal anesthesia.
The efficacy and safety of intravenous metoclopramide administered prophylactically before elective cesarean delivery under spinal anesthesia was studied. ⋯ Metoclopramide administered before induction of spinal anesthesia for cesarean delivery appears to significantly reduce both pre- and postdelivery emetic symptoms without apparent adverse effects on mother or neonate.
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Regional anesthesia · Mar 1992
Local anesthetic distribution in a spinal model: a possible mechanism of neurologic injury after continuous spinal anesthesia.
Cauda equina syndrome has been reported recently in patients receiving continuous spinal anesthesia using newly developed microcatheters (28 gauge). Failure of microcatheters to allow adequate mixing of local anesthetic was studied as a possible mechanism of the neurologic injury reported with these catheters. ⋯ Dependent drug concentrations were greater than those reported in the literature, capable of producing permanent neurologic injury. Directing the catheter tip in the nondependent direction and injecting lidocaine rapidly or through catheters with multiple end holes improved mixing and decreased dependent drug concentration.