Casopís lékar̆ů c̆eských
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Casopís lékar̆ů c̆eských · Jan 2011
[Preparation of the Eighth Framework Programme of the European Union--Health Priority. European Commission organizes proposal of aims in biomedical research prospecting to 2020].
Eighth framework programme (FP8) of the European Union for years 2014-2020 undergoes the preparatory process. The overview presents current status of the programme preparation. European Commission organized three workshops (-omics in personalised medicine, 4D biology for health and disease, and Stratification biomarkers in personalised medicine) with the purpose to bring together experts from different fields to build a 2020 vision, and to identify the research needs for next years.
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Casopís lékar̆ů c̆eských · Jan 2011
Biography Historical Article[Nobel Prize laureates. Robert William Holley (1922-1993)].
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Casopís lékar̆ů c̆eských · Jan 2011
Review[Hyperglycemia and its control in the critically ill patient].
In the critically ill patient, hyperglycemia was believed to be a response by the body to a stressful situation. Stress-induced hyperglycemia is the consequence of increased levels of cortisol, cytokines, growth hormones, catecholamines, and glucagon resulting in the stimulation of endogenous glucose production through glycogenolysis and gluconeogenesis as well as other mechanisms including central and peripheral insulin resistance. Among other things, hyperglycemia has an effect on inflammation and function of the myocardium, kidney, central nervous system, and the immune system. ⋯ The large multicenter NICE-SUGAR study in 6,022 patients showed higher 90-day mortality in the group with tight glycemic control. The results of NICE-SUGAR led to revision of the guidelines for glycemic control in the critically, recommending to control glycemia below 10 mmol/l. The aim of this overview is to summarize available data on glycemic control in the critically ill patient.
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Casopís lékar̆ů c̆eských · Jan 2011
Case Reports[Problems with placement and using of automated external defibrillators in Czech Republic].
The use of automated external defibrillators improves the survival of adults who suffer from cardiopulmonary arrest. Automated external defibrillators detect ventricular fibrillation with almost perfect sensitivity and specificity. Authors describe the use of automated external defibrillator during cardiopulmonary resuscitation in a patient with sudden cardiac arrest during ice-hockey match. The article reports also the use of automated external defibrillators in children.