Archives of pediatrics & adolescent medicine
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Arch Pediatr Adolesc Med · Nov 2009
Randomized Controlled TrialA randomized trial of nebulized 3% hypertonic saline with epinephrine in the treatment of acute bronchiolitis in the emergency department.
To determine whether nebulized 3% hypertonic saline with epinephrine is more effective than nebulized 0.9% saline with epinephrine in the treatment of bronchiolitis in the emergency department. ⋯ In the treatment of acute bronchiolitis, hypertonic saline and epinephrine did not improve clinical outcome any more than normal saline and epinephrine in the emergency setting. This differs from previously published results of outpatient and inpatient populations and merits further evaluation.
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Arch Pediatr Adolesc Med · Nov 2009
Multicenter StudyAntibacterial medication use during pregnancy and risk of birth defects: National Birth Defects Prevention Study.
To estimate the association between antibacterial medications and selected birth defects. ⋯ Reassuringly, penicillins, erythromycins, and cephalosporins, although used commonly by pregnant women, were not associated with many birth defects. Sulfonamides and nitrofurantoins were associated with several birth defects, indicating a need for additional scrutiny.
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Arch Pediatr Adolesc Med · Nov 2009
Parental views on withdrawing life-sustaining therapies in critically ill children.
To broaden existing knowledge of pediatric end-of-life decision making by exploring factors described by parents of patients in the pediatric intensive care unit (PICU) as important/influential if they were to consider withdrawing life-sustaining therapies. ⋯ Parents describe a broad range of views regarding possible consideration of withdrawing life-sustaining therapies for their children and what factors might influence such a decision.
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Arch Pediatr Adolesc Med · Oct 2009
Multicenter StudyEnd-of-life decisions in Dutch neonatal intensive care units.
To clarify the practice of end-of-life decision making in severely ill newborns. ⋯ Virtually all deaths in Dutch neonatal intensive care units are preceded by the decision to withdraw life-sustaining treatment and many decisions are based on future quality of life. The decision to deliberately end the life of a newborn may occur less frequently than was previously assumed.