Archives of pediatrics & adolescent medicine
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Arch Pediatr Adolesc Med · Jan 2009
Review Meta AnalysisCerebral palsy, autism spectrum disorders, and developmental delay in children born after assisted conception: a systematic review and meta-analysis.
To assess the existing evidence of associations between assisted conception and cerebral palsy (CP), autism spectrum disorders (ASD), and developmental delay. ⋯ Methodological problems were revealed in the identified studies, and the gaps in our knowledge about the long-term outcomes of children born after assisted conception are considerable, including a lack of information on the long-term consequences of ovulation induction. Possible associations with ASD and developmental delay need assessment in larger studies. Studies on assisted conception and CP from countries outside of Scandinavia are needed, including detailed information on time to pregnancy, underlying cause of infertility, and type of IVF treatment.
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Arch Pediatr Adolesc Med · Jan 2009
Comparative StudyDiagnosis of neonatal sepsis using universal primer polymerase chain reaction before and after starting antibiotic drug therapy.
To study universal primer 16S rRNA gene polymerase chain reaction (PCR) for diagnosis of blood culture-positive neonatal sepsis before and after starting antibiotic drug therapy. ⋯ Universal primer PCR can accurately diagnose neonatal sepsis before but not after antibiotic drugs are given.
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Arch Pediatr Adolesc Med · Jan 2009
Multicenter Study Comparative StudyPrevalence of low back pain and its effect on health-related quality of life in adolescents.
To assess the prevalence of low back pain (LBP) in adolescents and the clinical features of LBP in 2 European countries and to evaluate the effect of LBP on health-related quality of life (HRQOL) using standardized validated generic and disease-specific instruments. ⋯ Low back pain in adolescents is a prevalent symptom with overall low associated disability and little effect on health-related quality of life. A subset of adolescents in whom LBP is associated with whole-body pain report significant impairment and deserve more attention.
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Arch Pediatr Adolesc Med · Jan 2009
Comparative StudyRespite care for children with special health care needs.
To describe (1) the subpopulation of children with special health care needs (CSHCN) in need of respite care and (2) the factors associated with unmet respite care needs. ⋯ Respite care needs of CSHCN are frequently unmet. Furthermore, strategies are needed to improve access to respite care for families of CSHCN.