Anales españoles de pediatría
-
In order to evaluate the programs of vaccination against tetanus, we have studied the presence of specific antibodies in a sample of children and adolescents from our region. We used a passive hemagglutination test, corroborating the results by a biological assay based on toxin-neutralization. Among the subjects investigated, 93.2% (551/591) had neutralizing toxin-antibodies at a protective level (> or = 0.01 ui/ml). ⋯ The results show an excellent immunization coverage among the childhood population in our region. They also confirm the high effectiveness of this vaccine. However, this high protection was not found among people above the adolescent period.