Revista médica de Chile
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The evaluation of renal function in older adults is usually carried out with a creatinine clearance or an estimation of glomerular filtration rate using formulas such as Cockcroft-Gault, MDRD or CKD-EPI. The results obtained with these formulas are often regarded as equivalent. However, in adults older than 70 years, the Cockcroft-Gault formula frequently underestimates the glomerular filtration rate with respect to reference methods and the MDRD formula overestimates it. ⋯ Also, when kidney function is overestimated, CKD patients are prevented from receiving the treatments appropriate for their condition. In recent years, new formulas have been proposed (FAS, BIS) with a greater accuracy to estimate glomerular filtration rate in older adults. This review describes the behavior of these formulas in a significant number of older adults, from various countries, and proposes using those equations with the best performance in older adults.
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Revista médica de Chile · Mar 2021
The resurgence of syphilis among pregnant women in southern Chile.
National rates of HIV, gonorrhoeae and syphilis have increased in Chile in recent years, but it is not known if syphilis among pregnant women (PW) is also escalating. ⋯ Resurgence of syphilis among pregnant women is happening in southern Chile and is associated to adverse-pregnancy outcomes.
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Revista médica de Chile · Mar 2021
Case Reports[Small bowel obstruction caused by lymph nodes of a neuroendocrine tumor. A clinical case report].
Small intestine neuroendocrine tumors (NET-SI) are relatively rare neoplasms. If encountered, the most common location is the ileum. Symptoms are usually non-specific, delaying the tumors diagnosis. ⋯ The patient also presented multiple peritoneal metastases at diagnosis. Characteristic imaging findings of the tumor, allowed an accurate and early diagnosis. Once the acute episode was resolved, the diagnosis was confirmed with an image guided biopsy.
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Revista médica de Chile · Mar 2021
[Prevalence and repercussions of the locomotor syndrome in patients with chronic obstructive pulmonary disease].
Patients with Chronic Obstructive Pulmonary Disease (COPD) suffer a progressive deterioration of functional status and a decrease in independence in activities of daily living. Locomotor Syndrome (SL) is the involvement of the musculoskeletal system due to the deterioration caused by age. ⋯ LS in patients with COPD impacts their functional status and quality of life.
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Revista médica de Chile · Mar 2021
Observational Study[Vitamin D levels in patients with inflammatory bowel disease].
Inflammatory Bowell Diseases (IBD), either ulcerative colitis (UC) or Chron's disease (CD) are commonly associated with intestinal malabsorption, and insufficient levels 1-25 hydroxycholecalciferol (vitamin D). These insufficient levels could be linked with an increased risk of clinical disease activity. ⋯ These patients with IBD had a high frequency of hypovitaminosis D.