Mayo Clinic proceedings
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Mayo Clinic proceedings · Apr 2012
Meta Analysis Comparative StudyMeta-analysis of randomized controlled trials of vancomycin for the treatment of patients with gram-positive infections: focus on the study design.
To study the effectiveness and safety of vancomycin compared with that of other antibiotics for the treatment of gram-positive infections. ⋯ On the basis mainly of data from open-label trials, vancomycin is a treatment choice that is as effective as other available antibiotics for patients with gram-positive infections. Study design seems to make a major contribution to the outcome.
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Nocardia, a gram-positive bacillus with the microscopic appearance of branching hyphae, can produce considerable disease in the appropriate host. The taxonomy of Nocardia continues to evolve; more than 50 species have been described. ⋯ Although nocardiosis typically occurs in patients with cell-mediated immunosuppressive conditions, infection may occasionally develop in immunocompetent patients as well. This review addresses the microbiology of Nocardia, risk factors for infection, clinical presentations, and management strategies.
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Mayo Clinic proceedings · Apr 2012
Total knee arthroplasty outcomes in top-ranked and non-top-ranked orthopedic hospitals: an analysis of Medicare administrative data.
To examine outcomes of Medicare enrollees who underwent primary total knee arthroplasty (TKA) in top-ranked orthopedic hospitals identified through the U.S. News & World Report hospital rankings and 2 comparison groups of hospitals. ⋯ Rates of postoperative complications and readmission and hospital LOS were similar for Medicare patients who underwent primary TKA in top-ranked and non-top-ranked hospitals.
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Mayo Clinic proceedings · Apr 2012
Service census caps and unit-based admissions: resident workload, conference attendance, duty hour compliance, and patient safety.
To examine the effect of census caps and unit-based admissions on resident workload, conference attendance, duty hour compliance, and patient safety. ⋯ Census caps and unit-based admissions were associated with improvements in resident workload, conference attendance, duty hour compliance, and readmission rates while patient outcomes were maintained.
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Mayo Clinic proceedings · Apr 2012
Increasing incidence of melanoma among young adults: an epidemiological study in Olmsted County, Minnesota.
To identify the change in the incidence of cutaneous melanoma over time among young adults. ⋯ The incidence of cutaneous melanoma among young adults is rapidly increasing, especially among women. Continued close monitoring of this high-risk population is necessary.