Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
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Zh Vopr Neirokhir Im N N Burdenko · Mar 1990
Comparative Study[The combined therapy of patients with severe craniocerebral injury].
The hemostasis system was studied in 423 patients. Coagulation occurred in a definite sequence: its expressiveness and duration were determined by the severity and form of brain damage. In the period of hypercoagulative changes (from 2 to 15 days and longer), thrombotic processes were revealed in 16% of the cases. Anticoagulative treatment including heparin, indirect anticoagulants, des- and antiaggregates, as well as fibrinolytics were applied in 27% of the cases, which reduced mortality by 12%.