The Journal of infectious diseases

The most recent articles from: J. Infect. Dis. June 2007

J. Infect. Dis. · Jun 2007

Characterization of CD4+ memory T cell responses directed against common respiratory pathogens in peripheral blood and lung.

We investigated CD4(+) memory T cell responses to influenza virus (FLU), respiratory syncytial virus (RSV), and nontypeable Haemophilus influenzae (NTHi). ⋯ No gross defects were found in circulating CD4(+) memory cells specific for pathogens associated with COPD. However, the large differentiated CD4(+) memory T cell pool residing in the lung may contribute to a large extent to local antiviral immunological protection.

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