The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
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J Pediatr Pharmacol Ther · Mar 2019
Population Pharmacokinetics of Vancomycin in the Pediatric Cardiac Surgical Population.
Vancomycin is often used in the pediatric cardiac surgical population, but few pharmacokinetic data are available to guide dosing. ⋯ Vancomycin dosing in the postoperative pediatric cardiac surgical population should incorporate postmenstrual age and creatinine clearance. A vancomycin dose of 20 mg/kg every 8 hours is a reasonable empiric strategy.