Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
-
Zhongguo Zhong Yao Za Zhi · Sep 2013
[Analysis of actual effects of combining xiyanping injection with vitamin C injection in treatment of upper respiratory tract infection].
To investigate whether Xiyanping injection associated with vitamin C injection will improve the cure rate of upper respiratory tract infection compared to treatment with Xiyanping injection alone. ⋯ Compared with Xiyanping injection alone, using vitamin C in combination does not improve the treatment effectiveness of upper respiratory tract infection.
-
Zhongguo Zhong Yao Za Zhi · Sep 2013
[Pharmacovigilance of parenterally administered salvianolate based on analysis of spontaneous reporting system data].
Spontaneous reporting system (SRS) is currently a basic method to monitor and find adverse drug reactions (ADR) signals used worldwide. This method can promptly and effectively discover ADR signals and is of great significance to effectively prevent and avoid ADRs. Parenterally administered salvianolate has the functions of activating blood circulation and removing stasis. ⋯ The drugs early warning signs were dizziness, headache, nausea, itchiness and rash estimated using PRR. Early warning signs based on BCPNN were dizziness and headache. The ADRs of dizziness and headache are early warning signals associated with the nervous system.
-
Zhongguo Zhong Yao Za Zhi · Sep 2013
Review Meta Analysis[Systematic review of shenfu injection for septic shock].
To assess the efficacy and safety of Shenfu injection for septic shock. All clinical studies of Shenfu injection for septic shock were searched from Cochrane library, Medline, EMbase, CBM, CNKI, Wanfang and VIP. Quality assessment and information extraction were done by two independent screening. ⋯ This study may exist publication bias. Shenfu injection on the basis of conventional treatment can improve blood pressure of the treatment of septic shock; we can not get a positive conclusion in improving shock symptom and HR. Also, due to the sample size of included studies were small and of lower quality, conclusions above still need high-qualitied randomized, double-blind, controlled trials be confirmed.
-
Zhongguo Zhong Yao Za Zhi · Sep 2013
[Explore dengzhan xixin injection effecting on outcome of coronary heart disease based on propensity score].
Records of 2 325 patients with CHD were extracted from 20 hostpial information systems, who were divided into two groups, one group has 768 patients using Dengzhan Xixin, the other group has 1 557 patients without using Dengzhan Xixin. Using generalized boosted models (GBM) with propensity scores to balance confounding factors and using three Logistic regressions to analysis the cure rates of coronary heart disease. ⋯ Propensity score could be a good method to balance confounding factors in a retrospective data analysis. However it is not a prospective research, the information from this study should be carefully referred to.
-
Zhongguo Zhong Yao Za Zhi · Sep 2013
Guideline[Interpretation of Guidelines on Good Pharmacovigilance Practices for European Union].
Due to the limitations of pre-authorization clinical trials, the safety information obtained from them is relatively limited. Therefore, it is very necessary to carry out pharmacovigilance activities on drugs post-marketing. ⋯ In addition, it set more specific and comprehensive requirements on risk management systems, the management and reporting of adverse reactions to medicinal products, periodic safety update reports, post-authorization safety studies, signal management, and so on. Interpreting the basic principles, working mechanisms, key technologies and methods of the GVP provides a useful reference for us to carry out pharmacovigilance (especially regarding safety monitoring of parenterally administered Chinese medicine).