The Lancet. Global health
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The Lancet. Global health · May 2018
National and regional under-5 mortality rate by economic status for low-income and middle-income countries: a systematic assessment.
The progress to achieve the fourth Millennium Development Goal in reducing mortality rate in children younger than 5 years since 1990 has been remarkable. However, work remains to be done in the Sustainable Development Goal era. Estimates of under-5 mortality rates at the national level can hide disparities within countries. We assessed disparities in under-5 mortality rates by household economic status in low-income and middle-income countries (LMICs). ⋯ National University of Singapore, UN Children's Fund, United States Agency for International Development, and the Bill & Melinda Gates Foundation.
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The Lancet. Global health · May 2018
Randomized Controlled TrialOral doxycycline for the prevention of postoperative trachomatous trichiasis in Ethiopia: a randomised, double-blind, placebo-controlled trial.
Trachomatous trichiasis is treated surgically to prevent sight loss. Unfavourable surgical outcomes remain a major challenge. We investigated the hypothesis that doxycycline might reduce the risk of postoperative trichiasis following surgery in patients with trachomatous trichiasis through anti-matrix metalloproteinase and anti-inflammatory activity. ⋯ The Wellcome Trust.
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The Lancet. Global health · May 2018
Randomized Controlled TrialEffect of self-administration versus provider-administered injection of subcutaneous depot medroxyprogesterone acetate on continuation rates in Malawi: a randomised controlled trial.
Injectable contraceptives are popular in sub-Saharan Africa but have high discontinuation rates due partly to the need for provider-administered re-injection. We compared continuation rates of women who self-injected subcutaneous depot medroxyprogesterone acetate (DMPA-SC) and women who received DMPA-SC from a health-care provider, including community health workers (CHWs). ⋯ United States Agency for International Development and Children's Investment Fund Foundation.
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The Lancet. Global health · May 2018
Risk of maternal mortality in women with severe anaemia during pregnancy and post partum: a multilevel analysis.
Anaemia affects as many as half of all pregnant women in low-income and middle-income countries, but the burden of disease and associated maternal mortality are not robustly quantified. We aimed to assess the association between severe anaemia and maternal death with data from the WHO Multicountry Survey on maternal and newborn health. ⋯ Barts and the London Charity.