Zhonghua yi xue za zhi = Chinese medical journal; Free China ed
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Zhonghua Yi Xue Za Zhi (Taipei) · Apr 1995
Randomized Controlled Trial Comparative Study Clinical TrialVecuronium dissolved in normal saline exaggerates pain on intravenous injection.
On some anesthetic occasions, many patients complained of pain at the site of injection when vecuronium, dissolved in normal saline, was administered intravenously. The aims of this study was to compare the incidence of pain on i.v. injection of vecuronium either dissolved in normal saline or in a solvent provided by the pharmaceutical manufacturer. ⋯ Pain resulting from intravenous injection of vecuronium can be aggravated if normal saline was used as the solvent. Increased osmolality may also be responsible for this phenomenon.