Journal of neurology
-
Journal of neurology · Jan 2007
Bilateral subthalamic nucleus stimulation in advanced Parkinson's disease: three years follow-up.
To assess the long-term efficacy and safety of chronic bilateral stimulation of the subthalamic nucleus (STN) in patients with advanced Parkinson's disease (PD). ⋯ Our data demonstrate that: 1) bilateral STN stimulation is relatively safe, improves the motor symptoms and drug-related motor complications of PD, and reduces the daily dosage of medication; 2) this benefit is sustained over time despite the occurrence of axial doparesistant signs in some patients.