Deutsche medizinische Wochenschrift
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Dtsch. Med. Wochenschr. · Sep 2024
Comparative Study[Comparison of LDL cholesterol serum concentrations in patients after acute coronary syndrome between 2018 and 2022 in Germany and Europe].
ESC/EAS guidelines for the management of dyslipidemia after acute coronary syndrome (ACS) were updated in 2019 with lower LDL cholesterol (LDL-C) goals. Their effect on LDL-C lowering in Germany and across Europe is not known. The EuroPath IV survey was designed to compare the lipid management in patients post ACS in the year 2022 with 2018. ⋯ Achievement of LDL-C goals improved after the update of the ESC/EAS lipid guidelines in 2019 but LDL-C goal achievement remains still very low. Even less patients in Germany achieved the LDL-C goals compared to other European countries.
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Dtsch. Med. Wochenschr. · Sep 2024
[Skin changes around wounds: A position paper from the professional society Initiative Chronische Wunden (ICW) e.V.].
Many patients with chronic wounds have skin changes that can provide important clues as to the etiology of the wound and/or inappropriate treatment. As the largest human organ, the skin is easily accessible for clinical inspection. ⋯ One focus here is on the definition and differentiated description of the wound edge and wound surrounding skin. Atrophies, blisters, eczema, erythema, hemorrhages, hyperpigmentation, hypopigmentation, hyperkeratosis, maceration, necrosis, oedema, pustules, sclerosis and scales are then described in more detail and placed in a clinical context.
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Dtsch. Med. Wochenschr. · Sep 2024
[Shortfalls of new data 2017-2020 in the German transplant registry].
Recently, considerable deficiencies of legacy data (2006–2016) of the newly established German Transplant Registry were described. Current data (2017–2020) of the registry are subject to the present assessment. ⋯ The German Transplant Registry needs to be fundamentally reorganized. Above all, the mandatory consent to data storage and the uncritical inclusion of data provided by various institutions render the current registry useless.
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Dtsch. Med. Wochenschr. · Sep 2024
[Importance and prevalence of multidrug-resistant gram-negative bacteria in Germany].
Infections with multidrug-resistant gram-negative bacterial species are a great concern in clinics in Germany. By limiting therapeutic options dramatically, these bacteria pose a significant threat to patient health and cause extensive pressure on hygiene systems and patient management. ⋯ According to established surveillance systems like national reporting systems, KISS or the National Reference Centre, multidrug-resistant bacteria are constantly on the rise in Germany. Although several novel therapeutic options have been approved recently, these bacteria represent a constant challenge and it may be necessary to discuss if the present hygiene recommendations need an update for an efficient and targeted prevention of transmission.
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Dtsch. Med. Wochenschr. · Sep 2024
[Multi-resistant bacteria - epidemiological trends and new treatment options].
Multi-resistant bacteria such as Escherichia coli and Klebsiella pneumoniae are a growing threat worldwide. The spread of Carbapenemase-producing strains is particularly worrying. New antibiotics and combination therapies offer treatment options, but the development of resistant pathogens remains a major challenge.