Therapia Hungarica (English edition)
-
The conjunctival bacterium flora was examined during the preoperative and postoperative treatment of 200 patients who underwent intraocular surgery. Brulamycin eye drops (15 mg tobramycinum in 5 ml solution) were given to 100 patients and Oculogutta neomycin (50 mg neomycinum sulfuricum in 100 ml solution) to 100 patients. The effectivity, objective and subjective side-effects of the two drugs, and resistance to the drugs were examined. On the basis of comparative data and the observations of the authors, Brulamycin eye drops are recommended for the premedication of intraocular surgery.
-
Norcuron has been used for intubation and short-term relaxation in 21 cases and for maintaining neuromuscular blockade during major operations of 48 patients suffering from severe clinical conditions. The drug assured in all cases relaxation for the required period and longer operations could also be performed, if required, with the repetition of doses. According to the observations Norcuron proved to be a muscle relaxant of medium duration of action which may be combined with drugs commonly used for premedication, as well as with narcotics introducing and maintaining anaesthesia. The special advantage of the drug is that virtually it does not influence the circulatory parameters and its action may be reliably antagonized.
-
Norcuron, a new, non-depolarizing muscle relaxant has been used for anaesthesia of 48 obstetrical and gynaecological operations. The product could assure the required neuromuscular blockade in all discussed operation types when given either in single or repeated doses. ⋯ The drug had no unfavourable circulation influencing side-effect and could be combined with the used anaesthetics. In newborns delivered by Caesarean section pathological changes were observed nor in Apgar scores, neither in the cardiorespiratory adaptation.
-
Vecuronium bromide (Norcuron) has been used as an intubation and surgical muscle relaxant besides the use of different types of anaesthesia in the course of 230 gynaecological operations. With a single or repeated drug dose complete muscular relaxation could be assured during operation of 25-60-minute duration. In general the clinical muscle relaxant action lasted for about 30 minutes. ⋯ The drug could be combined with anaesthetics without risk. Cardiovascular unwanted effects or other after-effects did not occur. According to the author-s opinion, as a neuromuscular blocker of a short to medium duration of action, Norcuron is a long-needed drug in Hungarain anaesthesiological practice.
-
Norcuron, a neuromuscular blocking agent of medium duration of action has been applied to 50 general surgery patients. The muscle relaxant assured the muscle relaxation required for performing operations of 25'-180' duration, if required by repeating the drug administration. ⋯ In spite of the relative overdosage used by the author unexpected phenomenon did not occur and the unwanted effects of Norcuron did not develop. The product is a myorelaxant which may be safely and flexibly used and the doses of which may be easily changed.