Therapia Hungarica (English edition)
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Vecuronium bromide (Norcuron) has been used as an intubation and surgical muscle relaxant besides the use of different types of anaesthesia in the course of 230 gynaecological operations. With a single or repeated drug dose complete muscular relaxation could be assured during operation of 25-60-minute duration. In general the clinical muscle relaxant action lasted for about 30 minutes. ⋯ The drug could be combined with anaesthetics without risk. Cardiovascular unwanted effects or other after-effects did not occur. According to the author-s opinion, as a neuromuscular blocker of a short to medium duration of action, Norcuron is a long-needed drug in Hungarain anaesthesiological practice.
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Norcuron, a neuromuscular blocking agent of medium duration of action has been applied to 50 general surgery patients. The muscle relaxant assured the muscle relaxation required for performing operations of 25'-180' duration, if required by repeating the drug administration. ⋯ In spite of the relative overdosage used by the author unexpected phenomenon did not occur and the unwanted effects of Norcuron did not develop. The product is a myorelaxant which may be safely and flexibly used and the doses of which may be easily changed.