Pain medicine : the official journal of the American Academy of Pain Medicine
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Case Reports
Rapid-onset opioids for the treatment of breakthrough cancer pain: two cases of drug abuse.
In the last few years, the use of opioids for cancer pain has rapidly increased and new molecules have been developed. Currently, rapid-onset opioids are widely used in clinical practice for breakthrough cancer pain (BTcP). However, the tolerability of these molecules is still a matter of debate. ⋯ The reported cases are explicative as they occurred in patients suffering from different types of cancer and with different causes of BTcP. Further investigations are needed to identify factors predicting addiction to this new class of molecules.
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The aim of this study was to investigate the clinical characteristics of primary stabbing headache (PSH) and its prevalence in a neurology outpatient center at a university hospital in China. ⋯ PSH was shown to have an onset at middle age with moderate-to-severe intensity attacks localized predominantly within the first division of the trigeminal nerve. Accompanying phenomena and trigger factors were common and should be noted, implying further research to be conducted.