[Hokkaido igaku zasshi] The Hokkaido journal of medical science
-
Hokkaido Igaku Zasshi · Mar 1990
[Spinal cord evoked potential in experimental spinal cord injury--the changes in spinal cord evoked potential following impact injury, and effect of mannitol administration on acute experimental spinal cord injury].
The authors reported the changes of spinal cord evoked potential following impact injury by the weight dropping technique in untreated and treated animals. The correlation between the change in amplitude of the spinal cord evoked potential after injury and the prognosis for motor recovery of legs was also discussed. (Materials and Methods) The spinal cord of 57 adult dogs was traumatized by the weight dropping technique at the level of Th10. 37 dogs were not treated. The trauma consisted of 300 gm-cm impact injury, 400 gm-cm impact injury and 500 gm-cm impact injury. ⋯ However, the precise prognosis for motor recovery could not be accurately estimated in dogs with recovery of amplitude between 39% and 20%. 3. In mannitol-treated group with intravenous continuous infusion, the recovery of the amplitude was superior to that in untreated group at a significance level of p less than 0.05. However, in the group with intravenous bolus injection of mannitol, the recovery was transient.