Laboratory animals
-
Comparative Study
Induction of anaesthesia with halothane and isoflurane in the rabbit: a comparison of the use of a face-mask or an anaesthetic chamber.
The effects of induction of anaesthesia with halothane or isoflurane were studied in rabbits. The anaesthetic agents were delivered either via a face-mask, or the animals were placed in an anaesthetic induction chamber. ⋯ The combination of bradycardia and hypercapnia during induction may represent an increased risk of anaesthetic associated mortality. Animals in all groups tried to avoid inhaling anaesthetic vapour, and this behaviour, together with the occurrence of breath-holding suggests that induction was aversive.
-
An anaesthetic mask for use on guinea pigs (Cavia porcellus) in a stereotaxic frame: technical note.
A mask was designed to allow inhalation anaesthesia to be used on guinea pigs (Cavia porcellus) whilst placed in a stereotaxic frame. To date, anaesthesia has been maintained in approximately 60 animals using this method, with no mortalities.
-
A safe and reliable technique for the endotracheal intubation of rabbits is described. Direct laryngoscopy is followed by intubation of the trachea with a fine catheter, and subsequent advancement of the endotracheal tube over this catheter.
-
Mean age at vaginal opening was 41 days, range 33-53 days. Bodyweight at weaning and age at vaginal opening were negatively correlated, but there was no relationship between bodyweight and age at vaginal opening. The presence of a male before vaginal opening did not accelerate either the time of its occurrence or first conception. The vaginas of females caged singly from weaning opened earlier than in those kept in groups of 2 or 3.
-
A surgical technique of performing tracheostomy in dogs requiring prolonged intubation with either cuffed or uncuffed tubes is described. Cannulae used in humans are anatomically unsuitable for the dog. The cannula and cuff described in this paper did not predispose to severe mechanical trauma to the trachea and we attempted to minimize factors that may predispose to tracheal damage during the period of intubation and the subsequent development of late tracheal injuring after extubation. A simple method of humidification in these healthy dogs proved adequate; neither tenacious tracheobronchial secretion nor the retention of secretions were seen.