Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
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J Microbiol Immunol Infect · Aug 2009
The role of antimicrobial therapy for treatment of uncomplicated skin and soft tissue infections from community-acquired methicillin-resistant Staphylococcus aureus in children.
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections in skin and soft tissues are increasing in children in Taiwan. This study investigated the outcomes of therapy with or without appropriate antibiotics among children with CA-MRSA skin and soft tissue infections (SSTIs), and analyzed the outcomes of management among children with Panton-Valentine leukocidin (PVL)-positive strains and PVL-negative strains. ⋯ The high rate of successful treatment among children with uncomplicated CA-MRSA SSTIs, even when given inappropriate antibiotic therapy, suggests that treatment of these uncomplicated infections without appropriate antibiotic therapy is possible. Incision and drainage may play an important role in the treatment of uncomplicated SSTIs.