Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
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J Microbiol Immunol Infect · Aug 2007
Factors that affect sputum conversion and treatment outcome in patients with Mycobacterium avium-intracellulare complex pulmonary disease.
To investigate factors that might affect the sputum conversion and treatment outcome of Mycobacterium avium-intracellulare complex (MAC) pulmonary disease. ⋯ MAC pulmonary disease often occurs in the context of preexisting lung disease, especially pulmonary tuberculosis. Patients tend to be older. Inappropriate treatment might lead to failure of sputum conversion. Treatment with rational combination regimens for at least 5 months could be necessary for sputum conversion.
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J Microbiol Immunol Infect · Jun 2007
Case ReportsChromobacterium violaceum infection in Taiwan: a case report and literature review.
Chromobacterium violaceum is a facultative anaerobic, Gram-negative bacillus which inhabits stagnant water in tropical and subtropical regions. We describe the case of an 80-year-old female patient with C. violaceum bacteremia due to traumatic wound infected by contaminated water and soil. She had persistent fever, hypotension and neutrophilic leukocytosis on admission. ⋯ To our knowledge, six other cases have been reported previously from Taiwan, including two children and four adults. Of the total of seven patients from Taiwan, four had a fatal outcome within several days, while the three survivors were apparently free of vital organ involvement. Although human infections caused by C. violaceum are rare, clinicians should be aware of this potentially fatal infection as part of the differential diagnosis of sepsis associated with a history of exposure to stagnant water.
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J Microbiol Immunol Infect · Apr 2007
Comparative StudyComparison of in vitro activities of levofloxacin, ciprofloxacin, ceftazidime, cefepime, imipenem, and piperacillin-tazobactam against aerobic bacterial pathogens from patients with nosocomial infections.
There is a rapid worldwide emergence of multidrug-resistant pathogens, especially in nosocomial isolates. This study compared the in vitro activities of levofloxacin, ciprofloxacin, ceftazidime, cefepime, imipenem, and piperacillin-tazobactam against 208 aerobic bacterial pathogens that caused 197 nosocomial infections in 184 patients. ⋯ The majority of the bacterial isolates causing nosocomial infections were found to be sensitive to the 6 antibiotics tested. Bacterial isolates of nosocomial infections that were completely resistant to these 6 antibiotics were PDR A. baumannii, PDR P. aeruginosa, and oxacillin-resistant S. aureus. More potent antimicrobial agents are needed to treat infections caused by PDR A. baumannii and PDR P. aeruginosa.
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J Microbiol Immunol Infect · Feb 2007
Case ReportsSuccessful treatment of life-threatening melioidosis with activated protein C and meropenem.
Melioidosis is an endemic disease in southeast Asia and northern Australia, caused by Burkholderia pseudomallei. A typhoon-related outbreak occurred in southern Taiwan in July 2005. ⋯ We report a patient with life-threatening melioidosis who developed rapid progression of bacteremic pneumonia with acute respiratory distress syndrome, septic shock and multiple organ dysfunction and was successfully treated with recombinant human activated protein C (rhAPC) and meropenem. Although rhAPC has been reported to reduce the mortality of severe septic shock caused by various pathogens, to our best knowledge, this is the first reported case of rhAPC application in life-threatening melioidosis.
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J Microbiol Immunol Infect · Dec 2006
Case ReportsNecrotizing fasciitis caused by Shewanella putrefaciens in a uremic patient.
Shewanella putrefaciens rarely causes infections in humans. This report describes a case of necrotizing fasciitis caused by S. putrefaciens in a uremic patient who recovered in spite of inadequate antibiotic treatment. S. putrefaciens is a possible causative organism of necrotizing fasciitis, and the absence of any sign of systemic infection cannot rule out the possibility of invasive infection in uremic patients. Surgical intervention is important in such cases.