Veterinary anaesthesia and analgesia
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Randomized Controlled Trial Clinical Trial
Effects of pre- versus post-anaesthetic buprenorphine on propofol-anaesthetized rats.
To compare the effect of pre- versus post-anaesthetic intramuscular (IM) buprenorphine on intermittent intravenous (IV) propofol anaesthesia in rats. ⋯ Buprenorphine administration at the start of periodic IV propofol anaesthesia in rats resulted in a significant reduction in the total propofol requirement and significantly improved the 1-hour post-anaesthesia recovery score. Clinical relevance Besides the ethical advantage of pre-emptive analgesia, pre-anaesthetic medication with buprenorphine in rats significantly reduces the total propofol requirements for surgical anaesthesia and in this study was found to be a safe and effective method of anaesthesia.
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To review information on the pathogenesis, diagnosis and treatment of post-anaesthetic pulmonary oedema in horses. ⋯ Pubmed 1970-present, personal files.
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Randomized Controlled Trial Clinical Trial
Neuromuscular blocking properties of atracurium during sevoflurane or propofol anaesthesia in dogs.
To quantify the neuromuscular blockade (NMB) produced by atracurium in either sevoflurane or propofol-anaesthetized dogs. ⋯ Significant differences in the potentiation of NMB drugs are encountered with commonly used anaesthetics in the dog.
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Clinical Trial
Investigation of the EEG effects of intravenous lidocaine during halothane anaesthesia in ponies.
To record the electroencephalographic changes during castration in ponies anaesthetized with halothane and given intravenous (IV) lidocaine by infusion. The hypothesis tested was that in ponies, IV lidocaine is antinociceptive and would therefore obtund EEG changes during castration. ⋯ The antinociceptive effect of lidocaine combined with its minimal cardiovascular effects indicate a potential use for systemic lidocaine in clinical anaesthetic techniques.
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Clinical Trial
Use of lithium dilution and pulse contour analysis cardiac output determination in anaesthetized horses: a clinical evaluation.
To assess the suitability of a human algorithm for calculation of continuous cardiac output from the arterial pulse waveform, in anaesthetized horses. ⋯ This method of pulse contour analysis is a relatively noninvasive and reliable way of monitoring continuous Qt in the horse under anaesthesia. The ability to easily monitor Qt might decrease morbidity and mortality in the anaesthetized horse.