Swiss medical weekly
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Swiss medical weekly · Feb 1977
[Pulmonary humoral immune response after exposure to carbon monoxide].
The effect of exposure to CO was studied in guinea-pigs using the plaque forming cell technique. Exposure to 200 ppm for 5 weeks was found to reduce the capacity to produce IgG and IgM in free lung cells.
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The morphological pulmonary alterations in renal transplant recipients have been investigated in the light of 62 autopsies. Apart from the predominant pulmonary edema of septic, uremic or circulatory origin, pneumonic opportunistic infections were prominent. ⋯ At autopsy, pneumocystis carinii infections appeared to be of little importance. The pathology of the pulmonary changes reflects the reduced defense inevitably following on immunosuppressive medication, which in turn is indispensable for successful transplantation.