Articles: intensive-care-units.
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Review Meta Analysis
Outcomes of dexmedetomidine versus propofol sedation in critically ill adults requiring mechanical ventilation: a systematic review and meta-analysis of randomised controlled trials.
Guidelines have recommended the use of dexmedetomidine or propofol for sedation after cardiac surgery, and propofol monotherapy for other patients. Further outcome data are required for these drugs. ⋯ Dexmedetomidine did not significantly impact ICU length of stay compared with propofol, but it significantly reduced the duration of mechanical ventilation and the risk of delirium in cardiac surgical patients. It also significantly increased the risk of bradycardia across ICU patient subsets.
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Journal of critical care · Oct 2022
Meta AnalysisAssociation between timing of intubation and clinical outcomes of critically ill patients: A meta-analysis.
Optimal timing of intubation is controversial. We attempted to investigate the association between timing of intubation and clinical outcomes of critically ill patients. ⋯ Avoiding late intubation may be associated with lower mortality in critically ill patients without COVID-19.
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Journal of critical care · Oct 2022
Review Meta AnalysisSleep assessment in critically ill adults: A systematic review and meta-analysis.
To systematically review sleep evaluation, characterize sleep disruption, and explore effects of sleepdisruption on outcomes in adult ICU patients. ⋯ Sleep in critically ill patients is severely disturbed, and actigraphy and RCSQ seem reliable alternatives to PSG. Future studies should evaluate impact of sleep disruption on outcomes.