Articles: respiratory-distress-syndrome.
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Critical care medicine · Apr 1997
Comparative StudyPretreatment with inhaled nitric oxide inhibits neutrophil migration and oxidative activity resulting in attenuated sepsis-induced acute lung injury.
To determine if, and by what mechanisms, inhaled nitric oxide attenuates acute lung injury in a porcine model of adult respiratory distress syndrome induced by Gram-negative sepsis. ⋯ These results demonstrate that inhaled nitric oxide attenuates alveolar-capillary membrane injury in this porcine model of Gram-negative sepsis but does not adversely affect systemic hemodynamics. The data suggest that inhaled nitric oxide preserves alveolar-capillary membrane integrity by the following means: a) inhibiting transendothelial migration of activated, tightly adherent neutrophils; and b) possibly by attenuating the neutrophil oxidant burst.
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J. Heart Lung Transplant. · Apr 1997
Case ReportsExtracorporeal membrane oxygenation for early graft dysfunction in lung transplantation: a case report.
Although extracorporeal membrane oxygenation (ECMO) has become standard treatment for neonatal respiratory failure, the results of ECMO in adults have been less encouraging. With technical improvements in membrane oxygenators and revised ECMO protocols, there has been renewed interest in ECMO for adults with severe acute respiratory failure. ⋯ We present the case of a 20-year-old woman with cystic fibrosis who underwent bilateral single lung transplantation. She had development of severe graft dysfunction in the immediate postoperative period requiring support with ECMO for stabilization.
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Zhonghua Jie He He Hu Xi Za Zhi · Apr 1997
[Mechanical ventilation therapy with permissive hypercapnia on ARDS].
Study of mechanical ventilation (MV) therapy of ARDS (acute respiratory distress syndrome). ⋯ Using lower VT and permitting certain respiratory acidosis are worthy to be considered in MV therapy of ARDS.
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Zhonghua Jie He He Hu Xi Za Zhi · Apr 1997
[Effects of permissive hypercapnia on cardiopulmonary function in acute lung injury model].
To observe the effects of permissive hypercapnia on cardiopulmonary function in oleic acid induced acute lung injury (ALI) models. ⋯ It seems that mechanical ventilation with permissive hypercapnia was safe at certain level.