Articles: respiratory-distress-syndrome.
-
Intensive care medicine · Mar 1995
Randomized Controlled Trial Comparative Study Clinical TrialEffects of inhaled nitric oxide on right ventricular function in severe acute respiratory distress syndrome.
To compare the effects of inhaled nitric oxide (NO) and an infusion of prostacyclin (PGI2) on right ventricular function in patients with severe acute respiratory distress syndrome (ARDS). ⋯ Using a new approach to selective pulmonary vasodilation by inhalation of NO, we demonstrate in this group of ARDS patients that an increase in RVEF is not necessarily associated with a rise in CI. The increase in CI during PGI2 infusion is probably related to the systemic effect of this substance.
-
Arch Pediat Adol Med · Mar 1995
Comparative StudyOutcome of infants with birth weights less than 1000 g with respiratory distress syndrome treated with high-frequency ventilation and surfactant replacement therapy.
To compare outcomes in premature infants with respiratory distress syndrome who received surfactant replacement therapy and were treated with either high-frequency or conventional mechanical ventilation. ⋯ We conclude that high-frequency ventilation combined with surfactant therapy is as safe as conventional mechanical ventilation combined with surfactant therapy for treating respiratory distress syndrome in extremely low-birth-weight infants (< 1000 g) and does not increase the risk of either intraventricular hemorrhage or abnormal neurodevelopmental outcome.
-
To investigate the effects of inhaled nitric oxide (NO) in adult respiratory distress syndrome (ARDS) associated with a therapeutic optimization strategy on oxygen parameters, barotrauma, and evolution in a medical and surgical intensive care unit. ⋯ This study was shorter to demonstrate an improvement in the survival rate. Nevertheless, these preliminary results are encouraging. Because of its safety, effectiveness, and easy use, inhaled NO should be used as a part of a therapeutic optimization protocol before considering more invasive and expensive procedures, such as extracorporeal respiratory support or intravascular oxygenation.
-
Clinics in chest medicine · Mar 1995
ReviewPneumonia complicating adult respiratory distress syndrome.
Aspiration bronchopneumonia occurs in most patients undergoing prolonged mechanical ventilation. These pneumonias adversely affect lung function and release bacteria into the systemic circulation via the lungs' lymphatics. Through this mechanism, clinically occult pneumonias may initiate activation of systemic inflammation, leading to the syndrome of multiple organ failure.
-
Arch. Dis. Child. Fetal Neonatal Ed. · Mar 1995
Changes in oxygenation and heart rate after administration of artificial surfactant (ALEC) to preterm infants.
To determine if changes in oxygenation and heart rate occur after surfactant, changes in these variables were recorded continuously for 15 minutes before, during, and 15 minutes after the administration of the artificial surfactant ALEC to 21 preterm infants ventilated for respiratory distress syndrome. Median (range) birth weight and gestation were 1199 (561-2680) g and 28 (21-43) weeks, respectively. ⋯ No clinically important changes resulted from the administration of ALEC in the mean (SD) values for oxygen saturation (before 91.3 (3.4)%, during 90.7 (3.2)%, after 90.4 (3.7)% and heart rate (before 143 (15), during 138 (17), after 142 (16)). The maximum change in mean arterial oxygen saturation (SaO2) was a fall of 4.8%.