Randomized Controlled Trial

Topical menthol--a human model for cold pain by activation and sensitization of C nociceptors.

Brain. 2004 May 1;127(Pt 5):1159-71.
Randomized Controlled Trial

Heat, but not mechanical hyperalgesia, following adrenergic injections in normal human skin.

Pain. 2001 Feb 1;90(1-2):15-23.
Randomized Controlled Trial

Antihyperalgesic and analgesic properties of the N-methyl-D-aspartate (NMDA) receptor antagonist neramexane in a human surrogate model of neurogenic hyperalgesia.

Eur J Pain. 2008 Jan 1;12(1):17-29.