Randomized Controlled Trial

Daily sedation interruption in mechanically ventilated critically ill patients cared for with a sedation protocol: a randomized controlled trial.

JAMA. 2012 Nov 21; 308 (19): 1985-92.
Review

Sedation in the intensive care unit.

Minerva Anestesiol. 2012 Mar 1;78(3):369-80.
Comparative Study

Rapidly Reversible, Sedation-related Delirium versus Persistent Delirium in the ICU.

Am. J. Respir. Crit. Care Med. 2014 Mar 15; 189 (6): 658-65.