Comparative Study

Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.

Crit. Care Med. 2004 Aug 1;32(8):1637-42.
Comparative Study

Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock.

Crit. Care Med. 2009 May 1;37(5):1670-7.
Randomized Controlled Trial

Whole blood lactate kinetics in patients undergoing quantitative resuscitation for severe sepsis and septic shock.

Chest. 2013 Jun 1; 143 (6): 154815531548-1553.