• Statistics in medicine · Mar 2007

    A score test for overdispersion in zero-inflated poisson mixed regression model.

    • Liming Xiang, Andy H Lee, Kelvin K W Yau, and Geoffrey J McLachlan.
    • Department of Management Sciences, City University of Hong Kong, Kowloon.
    • Stat Med. 2007 Mar 30; 26 (7): 1608-22.

    AbstractCount data with extra zeros are common in many medical applications. The zero-inflated Poisson (ZIP) regression model is useful to analyse such data. For hierarchical or correlated count data where the observations are either clustered or represent repeated outcomes from individual subjects, a class of ZIP mixed regression models may be appropriate. However, the ZIP parameter estimates can be severely biased if the non-zero counts are overdispersed in relation to the Poisson distribution. In this paper, a score test is proposed for testing the ZIP mixed regression model against the zero-inflated negative binomial alternative. Sampling distribution and power of the test statistic are evaluated by simulation studies. The results show that the test statistic performs satisfactorily under a wide range of conditions. The test procedure is applied to pancreas disorder length of stay that comprised mainly same-day separations and simultaneous prolonged hospitalizations.Copyright (c) 2006 John Wiley & Sons, Ltd.

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