Gastrointestinal endoscopy
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Gastrointest. Endosc. · Sep 2013
Observational StudyA novel ingestible electronic drug delivery and monitoring device.
We developed an ingestible electronic drug delivery and monitoring system. This system includes an electronic capsule comprising a drug reservoir, a pH and temperature sensor, a microprocessor and wireless transceiver, a stepper motor, and batteries. The location of the capsule in the gut derived from pH data can be monitored in real time. The stepper motor can be remotely actuated to expel the contents of the drug reservoir. ⋯ This electronic drug delivery and monitoring system may be a promising tool for targeted delivery of substances to well-defined areas of the GI tract.
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Gastrointest. Endosc. · Jul 2013
Comparative StudyDelay in performing ERCP and adverse events increase the 30-day readmission risk in patients with acute cholangitis.
Readmission to the hospital within 30 days of discharge (30-day readmission rate) is used as a quality measure. ⋯ Delays in performing ERCP during the index admission, development of after-ERCP adverse events, and etiology of cholangitis not related to stones increased the risk of 30-day readmissions.
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Gastrointest. Endosc. · Jul 2013
Comparative Study Clinical TrialEffect of peroral endoscopic myotomy on esophagogastric junction physiology in patients with achalasia.
Pneumatic dilation and laparoscopic Heller myotomy improve parameters of esophageal function such as lower esophageal sphincter (LES) pressure, esophageal emptying, and esophagogastric junction (EGJ) distensibility. ⋯ POEM improves esophagogastric function and suggests favorable long-term results based on Eckardt score, esophageal manometry, esophageal emptying, and EGJ distensibility. Long-term follow-up of larger series will determine whether the high rate of reflux esophagitis affects the clinical application of POEM.