Gastrointestinal endoscopy
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Gastrointest. Endosc. · Nov 2006
An in vitro analysis of microbial transmission during EUS-guided FNA and the utility of sterilization agents.
The risk of infection and potential microbial transmission with EUS-guided FNA (EUS-FNA) of cystic lesions remains unknown. ⋯ EUS-FNA of sterile cystic lesions resulted in transmucosal microbial contamination. However, our model demonstrated that iodine sterilization of a contaminated mucosal surface produced a very highly statistically significant (P < .001) reduction in the transmission of infectious agents into a sterile environment. This in vitro model could translate into clinical practice by providing evidence that microbial transmission by FNA occurred. The utility of povidone iodine washings could alter procedure methods and patient care.
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Gastrointest. Endosc. · Oct 2006
Undernutrition is predictive of early mortality after palliative self-expanding metal stent insertion in patients with inoperable or recurrent esophageal cancer.
Self-expanding metallic stents (SEMS) are a first-line therapeutic procedure in the palliative treatment of dysphagia in patients with esophageal cancer. However, the impact of SEMS insertion on patient nutritional status has never been assessed. ⋯ This study suggested that palliative stent placement in esophageal cancer was effective to relieve dysphagia but was not followed by an improvement of nutritional parameters. Moreover, it underlined the key role played by undernutrition on survival.