Gastrointestinal endoscopy
-
Gastrointest. Endosc. · Feb 2004
Accuracy of EUS criteria and primary tumor site for identification of mediastinal lymph node metastasis from non-small-cell lung cancer.
EUS with FNA is useful for staging non-small-cell lung cancer. However, benign mediastinal adenopathy is common. The aims of this study were to identify clinical factors, especially primary tumor location, and EUS lymph nodal characteristics predictive of aortopulmonary window and subcarinal lymph node metastases of non-small-cell lung cancer. ⋯ Although tumor location and EUS lymph nodal characteristics are associated with malignant involvement of lymph nodes, the accuracy of these predictors does not obviate the need for cytologic evaluation. EUS with FNA should be performed for all lymph nodes when an abnormal finding will alter management.
-
Gastrointest. Endosc. · Dec 2003
Federal funding of endoscopic research in the United States: 1972-2002.
Funding for research is critical to the determination of appropriate applications for endoscopy in clinical practice. We sought to evaluate trends in funding provided by the National Institutes of Health (NIH) for endoscopic research from 1972 through 2002. ⋯ Funding for endoscopic research by the NIH has increased dramatically over the past 30 years, but it still lags behind funding in other fields. Projects focused on colorectal cancer, Barrett's esophagus, and optical technologies were most common among those funded, and the National Cancer Institute was the primary source of funding.
-
Gastrointest. Endosc. · Nov 2003
Propofol for endoscopic sedation: A protocol for safe and effective administration by the gastroenterologist.
There is increasing interest in the use of propofol, an ultrashort-acting hypnotic agent, for sedation during endoscopic examinations. A protocol was developed for administration of propofol, combined with small doses of midazolam and meperidine, for endoscopic sedation under the direction of a gastroenterologist. Initial experience with using this protocol is described. ⋯ On the basis of this initial experience, it is believed that propofol, potentiated by small doses of midazolam and meperidine, can be safely and effectively administered under the direction of a gastroenterologist. Additional research will be necessary to determine whether propofol is superior to the current methods of sedation.
-
Gastrointest. Endosc. · Oct 2003
Prospective evaluation of droperidol on sphincter of Oddi motility.
Droperidol increasingly is used as an effective adjunct for conscious sedation during endoscopic procedures. Given the concern for the effects of narcotics and benzodiazepines on sphincter of Oddi motility, and the potential difficulty in sedating patients undergoing sphincter of Oddi manometry, droperidol could be an ideal agent in this setting. ⋯ Droperidol alters basal sphincter pressures, which in some patients was clinically significant and would have resulted in misclassification. Although safe and well tolerated, droperidol appears to have subtle but clinically significant effects on the sphincter of Oddi.
-
Gastrointest. Endosc. · Aug 2003
Accuracy of magnifying endoscopy with methylene blue in the diagnosis of specialized intestinal metaplasia and short-segment Barrett's esophagus in Japanese patients without Helicobacter pylori infection.
The use of methylene blue chromoendoscopy in the diagnosis of specialized intestinal metaplasia in short-segment Barrett's esophagus is controversial. This study evaluated the use of magnifying endoscopy with methylene blue for this purpose. ⋯ Magnifying endoscopy with methylene blue selectively detects specialized intestinal metaplasia within short-segment columnar-lined esophagus.