Respiration; international review of thoracic diseases
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Systemic lupus erythematosus (SLE) can affect every organ. Involvement of the lungs in this disease is a significant cause of morbidity and mortality. ⋯ Our results indicated that determining the ratio of lung/liver uptake of (99m)Tc-HMPAO may be a useful complementary method to assess pulmonary injury in SLE patients.
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Following strenuous exercise, in vivo diaphragmatic strength has been reported to decrease. This decrease has been suggested to result from an increase in metabolic by-products of intense exercise. ⋯ This study suggests that physiological NH(3) concentrations do not adversely affect in vitro diaphragmatic contractility, fatigue, or recovery. These data are not consistent with diaphragmatic fatigue associated with exercise induced by arterial concentrations of NH(3) seen in humans, although further testing in situ or in vivo is needed.