Respiration; international review of thoracic diseases
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Existing prediction models for mortality in chronic obstructive pulmonary disease (COPD) patients have not yet been validated in primary care, which is where the majority of patients receive care. ⋯ The ADO index showed excellent prediction properties in an out-of-population validation carried out in COPD patients from primary care settings.
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The effect of obesity on outcomes in critically ill patients requiring invasive mechanical ventilation in a medical intensive care unit (ICU) is uncertain. ⋯ Obesity did not influence outcomes in critically ill patients requiring invasive mechanical ventilation in a medical ICU. Black obese patients had similar outcomes to black nonobese patients, and very obese patients also had similar outcomes to obese patients.
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Published data concerning the utility of computed tomography (CT)-based lung volumes are limited to correlation with lung function. ⋯ The CT Vratio had significant correlations with patient-centered outcomes and multidimensional COPD severity indices.
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Clinical Trial
Can lung ultrasound replace chest radiography for the diagnosis of pneumonia in hospitalized children?
Lung ultrasound is a non-radiating accurate alternative tool to chest X-ray (CXR) in the diagnosis of community-acquired pneumonia (CAP) in adults. ⋯ In our series, lung ultrasound was highly accurate for the diagnosis of CAP in hospitalized children. These results provide the rationale for a multicenter study in children.
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Chronic obstructive pulmonary disease (COPD) is a major public health burden and profoundly affects individuals suffering from the disease. However, the majority of subjects with COPD are still undiagnosed. ⋯ COPD in the primary-care setting is as prevalent and underdiagnosed as reported recently for the BOLD study. The surprisingly low participation rate of GPs and patients indicates that prevention of COPD is not a health priority, and that awareness for COPD has to heightened before case-finding strategies will be successful.