The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
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J. Matern. Fetal. Neonatal. Med. · Jan 2016
Controlled Clinical TrialPolicy of high-dose tranexamic acid for treating postpartum hemorrhage after vaginal delivery.
To assess whether a policy of routine administration of high-dose tranexamic acid (TA) at the diagnosis of postpartum hemorrhage (PPH) reduces blood loss after vaginal birth. ⋯ A policy of high-dose TA in PPH after vaginal deliveries was not associated with a significant reduction of blood loss.
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J. Matern. Fetal. Neonatal. Med. · Jan 2016
Review Meta AnalysisCarbetocin for the prevention of postpartum hemorrhage: a systematic review and meta-analysis of randomized controlled trials.
To compare the efficacy and safety profile of carbetocin with other uterotonic agents in preventing postpartum hemorrhage. ⋯ Carbetocin has been associated with a similar low incidence of adverse effects to oxytocin and at least as effective as syntometrine and may become an alternative uterotonic agent for the prevention of postpartum hemorrhage. Further studies should be conducted to determine the safety and efficacy profile of carbetocin in women with cardiac disorders and to analyze the cost-effectiveness and minimum effective dose of carbetocin.
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J. Matern. Fetal. Neonatal. Med. · Jan 2016
Randomized Controlled TrialCarbetocin versus oxytocin for prevention of postpartum hemorrhage after vaginal delivery in high risk women.
To compare effectiveness and tolerability of carbetocin versus oxytocin in prevention of postpartum hemorrhage (PPH) after vaginal delivery. ⋯ Carbitocin is a better alternative to traditional oxytocin in prevention of PPH after vaginal delivery with minimal hemodynamic changes and similar side effects.
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J. Matern. Fetal. Neonatal. Med. · Jan 2016
Clinical TrialRole of presepsin in the diagnosis of late-onset neonatal sepsis in preterm infants.
One of the most challenging aspects in the management of neonates with late-onset neonatal sepsis (LOS) is to make the diagnosis. Presepsin is a novel and promising marker of sepsis. The aim of this study was to assess the role of presepsin in the diagnosis of LOS in preterm infants. ⋯ Presepsin can be used as a reliable biomarker for LOS and treatment response in preterm infants. However, we could not demonstrate the efficacy of presepsin for the detection of disease severity or prognosis.
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J. Matern. Fetal. Neonatal. Med. · Jan 2016
Early screening for critical congenital heart defects in asymptomatic newborns in Bursa province.
In this study, pulse oximetry screening results in the early diagnosis of critical congenital heart diseases (CCHD) will be evaluated. ⋯ The diagnosis of coarctation of the aorta is missed in the newborns screened with pulse oximetry in the first 24-48 h after birth. Screening with pulse oximetry should be repeated for early diagnosis of coarctation of the aorta.