Lancet neurology
The most recent articles from:
Lancet Neurol
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Randomised trials have shown that alteplase improves the odds of a good outcome when delivered within 4·5 h of acute ischaemic stroke. However, alteplase also increases the risk of intracerebral haemorrhage; we aimed to determine the proportional and absolute effects of alteplase on the risks of intracerebral haemorrhage, mortality, and functional impairment in different types of patients. ⋯ UK Medical Research Council, British Heart Foundation, University of Glasgow, University of Edinburgh.