Lancet neurology
The most recent articles from:
Lancet Neurol
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Meta Analysis
Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies.
The epilepsies are a clinically heterogeneous group of neurological disorders. Despite strong evidence for heritability, genome-wide association studies have had little success in identification of risk loci associated with epilepsy, probably because of relatively small sample sizes and insufficient power. We aimed to identify risk loci through meta-analyses of genome-wide association studies for all epilepsy and the two largest clinical subtypes (genetic generalised epilepsy and focal epilepsy). ⋯ International League Against Epilepsy and multiple governmental and philanthropic agencies.