Journal of spinal disorders & techniques
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J Spinal Disord Tech · Feb 2015
Incidental dural tear in cervical spine surgery: analysis of a nationwide database.
This was a retrospective study. ⋯ The incidence of DT in cervical spine surgery was 0.45% in the United States. The risk of DT was highest with a primary diagnosis of the ossification of the posterior longitudinal ligament (58.4 times). DT significantly increased the rate of in-hospital complications and health care burden.
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J Spinal Disord Tech · Feb 2015
The effect of bone morphogenetic protein-2 injection at different time points on intervertebral disk degeneration in a rat tail model.
Prospective in vivo rat tail model of disk degeneration comparing the effects of recombinant human bone morphogenetic protein-2 (rhBMP-2) injection over various time points and grades of degeneration. ⋯ rhBMP-2 injection of degenerated disks at 4 weeks postpuncture induced a transient improvement in disk grade on MRI and stimulated chondrogenic differentiation. These data suggest rhBMP-2 as a potential therapy for degenerative disk disease.