Ugeskrift for laeger
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Acceptable adverse effects and a clinical relevant weight loss of 3 to 5 kilograms have been found in long-term randomized clinical trials for sibutramine (Reductil) and orlistat (Xenical); these drugs may be prescribed for treatment of obesity for a duration of one and four years, respectively. This also seems to be the case for rimonabant (Acomplia), which is expected to receive approval in 2005 or 2006. However, until data on morbidity and mortality are available from RCTs, there is no absolute indication for prescribing drugs for treatment of obesity.
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During the last years huge amounts of literature have been reviewed systematically. Recently, guidelines have been proposed. ⋯ In this review we try to propose a rational approach to postoperative nausea and vomiting. The scoring of patients at risk, rational anaesthetic agents, prophylactic administration of antiemetics to patients at risk and effective postoperative antiemetic treatment are suggested.
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Ugeskrift for laeger · Dec 2005
Historical Article[Thirty four years of reports from the war against cancer].