Ugeskrift for laeger
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Ugeskrift for laeger · Jul 1997
Randomized Controlled Trial Clinical Trial[Effects of nitrogen oxide donor glyceryl trinitrate on pressure pain threshold in humans].
The purpose of the present study was to examine the effect of the nitric oxide (NO) donor glyceryl trinitrate (GTN) on nociceptive thresholds in man. On two different study days twelve healthy subjects received a stair case infusion of GTN (0.015, 0.25, 1.0, 2.0 micrograms/kg/min 20 min each dose) or placebo in a randomized double-blind cross-over design. Before the infusion and after 15 min of infusion on each dose, pressure pain detection- and tolerance thresholds were determined by pressure algometry in three different anatomic regions (finger, a temporal region with interposed myofascial tissue and a temporal region without interposed myofascial tissue). ⋯ No such changes were observed in the two other stimulated regions. These results could reflect central facilitation of nociception by NO. However, convergence of nociceptive input from pericranial myofascial tissue and from cephalic blood vessels dilated by NO may provide a more likely explanation.
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Ugeskrift for laeger · Jul 1997
Case Reports[Chronic unilateral maxillary sinusitis caused by foreign bodies in the maxillary sinus].
Chronic maxillary sinusitis is a common condition. The disease is most often caused by blockage of the sinus ostia or presence of an oroantral fistula. ⋯ In the first case the foreign body consisted of dental amalgam, in the second case of two silastic sponges left behind from a former operation because of "blowout" fracture. In the case of benign chronic maxillary sinusitis and foreign bodies, functional endoscopic sinus surgery (FESS) preceded by a CT-scan is an excellent approach, by which diagnosis as well as treatment can be achieved with minimal surgical trauma.
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The number of refugees around the world who have fled political or ethnic persecution has increased. An increasing proportion of these refugees are survivors of torture. Many of these suffer physical as well as psychological sequelae to torture. ⋯ After positional torture, in which the victims are suspended by their wrists which are tied behind their back (Palestinian hanging), severe lasting nerve, ligament, or tendon damage is seen. In this paper we present two cases of brachial plexus injury. Only sensory nerves were affected causing a neurogenic pain condition including dysaesthesia and neuralgia.
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Ugeskrift for laeger · Jun 1997
Randomized Controlled Trial Clinical Trial[The health project Ebeltoft: health check ups and discussions in general practice. Basic data from a 5-year, prospective, randomized, controlled population study].
A study was carried out to investigate people's interest in participating in health check-up and in discussions about health with their own general practitioner, participants' health status, the proportion who received health advice following health check-up, and the lifestyle goals they set following discussion with their general practitioner. This study reports the baseline data from a five-year randomized, controlled, prospective, population-based study in general practices in Ebeltoft, Denmark. All general practitioners from the four practices in Ebeltoft and a random sample of 2,000 people aged between 30 and 50 years were invited to participate. ⋯ Three out of four of those who had a health check-up were given health advice. Two out of three of those who were offered a health talk with the general practitioner appeared willing to make relevant lifestyle changes. Longterm follow up is needed to determine effects and side effects of health check-up and health talks.
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Awareness is a traumatic unintentional event during general anaesthesia. Awareness during anaesthesia is a condition which ranges from a state of alertness to deep anaesthesia with partly preserved senses. Awareness can be divided into four groups, depending on the state of alertness and accessibility of the memories after anaesthesia. ⋯ Guidelines to further reduce the incidence are suggested. Instant treatment of the condition may relieve the acute trauma and reduce the sequelae. We suggest a postoperative visit to ensure quality development for recording and treatment of awareness during anaesthesia.