Asian Pacific journal of cancer prevention : APJCP
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Asian Pac. J. Cancer Prev. · Jul 2018
Knowledge and Perception Towards Cervical Cancer among Female Debre Berhan University Students
Background: Cervical cancer is a global public health problem with around five hundred thirty thousand new cases and two hundred sixty five thousand deaths annually in 2015. Risky behaviors, lack of knowledge and preventative measures in young women, increase the risks of cervical cancer later in life. Up to date, there is scarcity of study on level of knowledge and perception towards cervical cancer among young women in Ethiopia. ⋯ Using radio and TV as source of information [AOR= 1.918 (95% CI: 1.223, 3.010)], having information about sexually transmitted infections (STI) [AOR =3.030 (95% CI: 1.665, 5.514)] were significantly and independently associated with good knowledge on cervical cancer. Conclusions: The level of knowledge towards cervical cancer and perception of acquiring the disease was poor. Health education interventions are needed to improve the awareness and health seeking behavior in youth women thereby preventing cervical cancer related morbidity and mortality.
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Asian Pac. J. Cancer Prev. · Jun 2018
Challenges in Indian Women’s Readiness to Quit Smokeless Tobacco Use
Introduction: In India, there are few cessation programs for women smokeless tobacco (SLT) users who want to quit. This paper uses Fishbein’s IM model to identify women SLT users’ challenges to quitting and multilevel correlates of “readiness to quit”. Methods: A survey of SLT use among women of reproductive age was conducted in 2010-13 in an urban slum community of Mumbai with a representative sample of 409 married women aged 18 to 40 years using at least one type of SLT daily. Data were analyzed using frequencies, bivariate statistics and logistic regression. ⋯ Correlates were positive beliefs and norms about SLT and withdrawal symptoms. Conclusions: Cessation programs should be made available to women, addressing correlates of women’s readiness to quit statuses. Results suggest the need for more complex social/contextual approaches to sustained cessation of SLT use including addressing depression and withdrawal, improved media messages and campaigns tailored to women, and support from family members.
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Asian Pac. J. Cancer Prev. · May 2018
Clinical TrialImpact of Double Expression of C-MYC/BCL2 Protein and Cell of Origin Subtypes on the Outcome among Patients with Diffuse Large B-Cell Lymphoma: a Single Asian Center Experience
Background: Diffuse large B-cell lymphoma (DLBCL) with double expression of c-MYC and BCL2 protein is associated with dismal outcome after treatment with R-CHOP. Local data on disease burden and survival outcome in DLBCL is limited. We investigated the prognostic values of c-MYC/BCL2 protein co-expression and cell of origin subtypes using immunohistochemistry (IHC) and to determine their associations with multiethnic groups under resource limited setting. ⋯ Indians had more DLBCL without c-MYC/ BCL2 protein co-expression compared to double-protein positive cases (66.7% vs 33.3%, P=0.414). Otherwise, the prognostic impact of ethnicity on survival outcome was insignificant (P=0.961). Conclusion: c-MYC/BCL2 protein co-expression in non-GCB subtype constituted a unique group with extremely inferior outcome regardless of ethnicity. Gene expression profile (GEP) may possibly provide insights into the cause of discrepancies in DLBCL subtypes and protein expression among the multiethnic groups.
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Asian Pac. J. Cancer Prev. · May 2018
Comparison of Salivary Cotinine Concentrations in Male Smokers and Smokeless Tobacco Users
Objective: Smoking cigarettes and smokeless tobacco are one of the causes of oral cancer. This study compared the salivary level of cotinine in male smokeless tobacco users and smokers. Methods: In this cross-sectional (descriptive-analytical) study, stimulated saliva samples from 30 male smokers and 30 male smokeless tobacco consumers were collected and their cotinine contents were measured using the competitive ELISA method according the standard curve. ⋯ Conclusion: Salivary levels of cotinine were not significantly different in smokeless tobacco users and cigarette smokers. In addition, increases in the number of cigarettes smoked and in pack of smokeless tobacco used, were associated with increased salivary levels of cotinine. The increase was higher in smokeless tobacco consumers.
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Asian Pac. J. Cancer Prev. · Mar 2018
Effects of an Educational Program for Prostate Cancer Prevention on knowledge and PSA Testing in Men Over 50 Years old in Community Areas of Shiraz in 2016
Background and Objectives: Prostate cancer was reported to be the second cause of cancer death in men in 2013. Studies have shown that those with higher knowledge levels are much more likely to undergo prostate cancer screening. The present study was aimed to determinate the effect of an educational program for prostate cancer prevention on knowledge and prostate-specific antigen (PSA) testing in men over 50 years old in community areas of Shiraz. Methods: This clinical trial was conducted among 93 men over 50 years old who were randomly divided into an intervention (n=48) and a control (n=45) group. The intervention group took part in an educational program focusing on the importance of prostate cancer prevention with emphasis on cultural and economic issues. ⋯ In addition, the intervention group’s mean score of knowledge increased by about 2.69 points after the intervention, and a significant difference was observed between the two groups in this regard (p<0.05). Conclusion: The results of the current study revealed effectiveness of the educational program in increasing the knowledge about prostate cancer and participation in PSA testing in men over 50 years of age. Hence, managers and authorities should execute plans to educate men regarding prostate cancer screening and promote their health status.