Interactive cardiovascular and thoracic surgery
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Interact Cardiovasc Thorac Surg · Jul 2015
Phenotypic switching of vascular smooth muscle cells in animal model of rat thoracic aortic aneurysm.
To explore if there is phenotypic switching in the vascular smooth muscle cells (vSMCs) of rat thoracic aortic aneurysms and the role it plays in the process of aneurysm formation. ⋯ There is vSMC phenotypic switching in animal models as seen through the rat thoracic aortic aneurysms. This may play an important role in the formation of aneurysms. Our findings are relevant to human aneurysms and may be conducive in the research of aortic aneurysm pathology and treatment.