Medicina clinica
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Major bleeding is a common complication of anticoagulant treatment. Risk assessment tools are relevant in the management of patients with atrial fibrillation and venous thromboembolism. The combination of clinical, biological and genetic markers is incorporated to build predictive scores to help in the decision process about intensity and duration of treatment. The optimal management of bleeding involves the application of predictive scores in combination with anticoagulant reversal strategies.
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Observational Study
Association between high-dose steroid therapy, respiratory function, and time to discharge in patients with COVID-19: Cohort study.
To analyze whether there is an association between the use glucocorticoids at high doses, and the evolution of saturation/fraction of inspired oxygen (SAFI) or time to discharge, in patients hospitalized with COVID-19. ⋯ We have not found improvement in respiratory function or time until discharge, associated with the use of glucocorticoids at high doses.
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Case Reports Observational Study
Statin therapy prior to hospitalization does not significantly influence sepsis presentation or sepsis outcomes. A prospective, observational study.
In addition to being effective at lowering cholesterol, statins seem to have immunomodulatory, antimicrobial, antioxidant and anticoagulant effects. ⋯ Statin therapy prior to hospitalization does not significantly influence sepsis presentation or sepsis outcomes.