Medicina clinica
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Letter Case Reports
Meningitis after prostatic abscess due to hypervirulent Klebsiella pneumoniae.
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Letter Case Reports
Marine-Lenhart syndrome as a cause of thyrotoxicosis: A case report.
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Letter Case Reports
Recurrent Polychondritis as a mimicker of challenging-to-manage allergic asthma.
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A review of the diagnostic and therapeutic management algorithm of the pathogen Clostridioides difficile for daily practice is presented. Its diagnosis, in any unformed stool sample sent to the laboratory, is based on a two-step algorithm, with demonstration of the pathogen by means of its enzyme glutamate dehydrogenase by immunoassay and subsequent PCR (polymerase chain reaction) of its toxin. The mainstay of step therapy, reserved for symptomatic patients, is fidaxomicin, over vancomycin. ⋯ Emerging therapies, such as faecal microbiota transplantation or the antibody bezlotoxumab, are gaining importance in patients with risk factors or relapses. Surgery is indicated in patients with worse prognosis and complications. Prevention is essential, based on vigilance and contact precautions, in addition to the elimination of spores from the environment.