Medicina clinica
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Mortality from COPD has decreased in Spain in recent years, but it is unknown whether this decline has been homogeneous among the different regions. ⋯ Mortality rates from COPD have decreased heterogeneously among the different Autonomous Communities in both men and women.
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ILD is a common manifestation in pSS and is associated with an increased risk of death. APCA are strongly expressed by hyperplastic alveolar epithelial cells in the fibrotic lung and are associated with an accelerated decline in lung function in IPF. In the present study, we aimed to evaluate the clinical utility of APCA in ILD patients with pSS. ⋯ APCA level is an independent risk factor and might be a potential biomarker for ILD in patients with pSS.