Medicina clinica
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Observational Study
Clinico-pathological evaluation of tumor budding in the oncological progression of colorectal cancer.
Tumor budding (TB), defined as the presence of individual neoplastic cells or isolated groups of up to 4 cells at the front of tumor invasion, has become an adverse prognostic marker in colorectal cancer (CRC) in recent decades. The prognostic impact of TB in CRC remains not clearly defined and histological methods for its evaluation vary depending on the center. The objective of this study is to investigate the association between TB and CRC, in terms of oncological evolution and pathological stage. ⋯ These results suggest that TB expression may be a useful risk factor as a prognostic factor for the detection of lymph node metastasis, local recurrence, and distant metastasis in CRC.
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Letter Case Reports
Intestinal pseudo-obstruction secondary to IgG4-related disease.
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Letter Case Reports
Pulmonary and mediastinal nocardiosis due to lymph node involvement.
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Multicenter Study
Classification tree obtained by artificial intelligence for the prediction of heart failure after acute coronary syndromes.
Coronary heart disease is the leading cause of heart failure (HF), and tools are needed to identify patients with a higher probability of developing HF after an acute coronary syndrome (ACS). Artificial intelligence (AI) has proven to be useful in identifying variables related to the development of cardiovascular complications. ⋯ The decision tree model, obtained by AI, identified 8 leading variables capable of predicting HF and generated 15 differentiated clinical patterns with respect to the probability of being hospitalized for HF. An electronic application was created and made available for free.