Eye & contact lens
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Multicenter Study Clinical Trial
Long-term clinical results: 3 years of up to 30-night continuous wear of lotrafilcon A silicone hydrogel and daily wear of low-Dk/t hydrogel lenses.
To summarize results of a 3-year clinical trial assessing subjective and objective experience with lotrafilcon A silicone hydrogel (SH) lenses for up to 30 nights of continuous wear or low-Dk/t daily-wear (LDW) hydrogel lenses. ⋯ During the 3 years, lotrafilcon A lens wearers who wore their lenses continuously for up to 30 nights showed stable, long-term improvements in many signs of corneal health and symptoms along with less myopic progression versus daily wearers of low-Dk/t hydrogel lenses. Many biomicroscopy signs and symptoms worsened among neophytes wearing daily-wear low-Dk/t hydrogel lenses. The use of lotrafilcon A lenses may minimize many ocular changes from soft contact lens wear.
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To compare the quality of vision of a bifocal rigid gas-permeable contact lens versus a bifocal soft contact lens in subjects with presbyopia. ⋯ Bifocal rigid gas-permeable contact lenses showed better visual performance than bifocal soft contact lenses did.
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To further analyze the possible causes of variability in spontaneous eye blink activity in apparently healthy humans. ⋯ Spontaneous eye blink activity can be rather different between healthy individuals, even under a single experimental condition. These differences do not appear to be caused by the time of day, mild symptoms, corneal sensitivity, age, or palpebral aperture features. In line with previous metaanalyses, it is therefore proposed that individuals could be grouped as to whether they have "normal" eye blink activity or be classified as having "frequent" eye blink activity. The latter group would include those who had an SEBR greater than 20 blinks per minute when assessed in primary eye gaze and in silence.
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Randomized Controlled Trial
Contact lens care products effect on corneal sensitivity and patient comfort.
To evaluate the possible effect of two leading soft contact lens care products on corneal sensitivity, relative comfort, and superficial corneal staining in adapted disposable soft contact lens wearers. ⋯ ReNu MultiPlus, a biguanide-based contact lens care product, was associated with decreased comfort during midday and end-of-day periods. ReNu MultiPlus was also associated with significant reduction in relative corneal sensitivity compared to Polyquad-based OPTI-FREE Express. Disturbance to normal corneal sensitivity may play a role in contact lens-related dry eye and discomfort. Further investigation is warranted.
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Comparative Study
Flammability of common ocular lubricants in an oxygen-rich environment.
Approximately 100 surgical fires take place in the United States each year. Recently, an ophthalmic lubricant was blamed for burning a child's eye while oxygen was administered during surgery. This study sought to determine whether four common ocular lubricants would ignite and sustain combustion in an oxygen-rich or standard room air environment. ⋯ The ocular lubricants in this experiment showed no detectable tendency to ignite, even with direct application of the ignition source. Factors such as body hair or oxygen pooling likely provided the conditions necessary for the surgical fire. Most importantly, the ophthalmic lubricants tested actually protected the corneal epithelium and decreased damage to the conjunctiva and lids.