Revista da Associacao Medica Brasileira (1992)
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Rev Assoc Med Bras (1992) · May 2020
NADPH Oxidase 5 upregulation is associated with lymphoma aggressiveness.
Lymphomas are a heterogeneous set of malignant neoplasias of lymphoid B and NK/T mature and immature cells at various stages of differentiation. Genetic and molecular biology tools are used to appropriately classify the type and prognosis of the lymphomas, which have implications in therapeutic effectiveness. Among them, the nicotinamide adenine dinucleotide phosphate-oxidase (NADPH) oxidase (NOX5) enzymes have been explored. This study analyzed the expression of NADPH oxidase 5 in lymphoma tissue according to the degree of tumor aggressiveness. ⋯ Aggressive lymphomas overexpress NOX5 protein. The higher NOX5 expression in aggressive lymphomas can suggest an involvement of this enzyme on the acquisition of an aggressive phenotype in lymphoid neoplasia.
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Rev Assoc Med Bras (1992) · May 2020
A significant relationship between personality traits and adhesive capsulitis.
We investigated the associations between adhesive capsulitis (AC) and a specific psychological profile. ⋯ We found a significant correlation between primary AC and particular personality traits, indicating an interaction between psychological and somatic factors.
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A covid-19 pandemic decreed by WHO has raised greater awareness of it. The infection reached the mark of 350,000 patients in 33 countries and affected as comorbidities the presence of comorbidities and advanced age. The transmissibility calculated so far is similar to the H1N1 epidemic, but with lower mortality rates. ⋯ In severe cases, the use of medications such as hydroxychloroquine and azithromycin or medication can be promising. Take care to avoid the use of corticosteroids. There are no restrictions on the use of resources and ACEIs / ARBs.